Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Comprehensive Income (Loss)
Balance, shares (in shares) at Dec. 31, 2021		81,886,965
Balance at Dec. 31, 2021	$ 417,890	$ 8	$ 1,639,476	$ (1,221,230)	$ (364)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common shares issued (in shares)		10,952,381
Common shares issued	433,718	$ 1	433,717
Exercise of stock options and issuances of restricted stock (in shares)		1,988,775
Exercise of stock options and issuances of restricted stock	21,441		21,441
Stock issued for services (in shares)		1,673
Stock issued for services	90		90
Share-based compensation	43,013		43,013
Net loss	(256,256)			(256,256)
Other comprehensive (loss) income	(3,826)				(3,826)
Balance, shares (in shares) at Dec. 31, 2022		94,829,794
Balance at Dec. 31, 2022	656,070	$ 9	2,137,737	(1,477,486)	(4,190)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Exercise of stock options and issuances of restricted stock (in shares)		1,548,468
Exercise of stock options and issuances of restricted stock	17,810		17,809
Stock issued for services (in shares)		1,549
Stock issued for services	92		92
Share-based compensation	52,832		52,832
Net loss	(139,674)			(139,674)
Other comprehensive (loss) income	4,294				4,294
Balance, shares (in shares) at Dec. 31, 2023		96,379,811
Balance at Dec. 31, 2023	591,424	$ 10	2,208,470	(1,617,160)	104
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common shares issued (in shares)		7,876,713
Common shares issued	543,086	$ 1	543,085
Exercise of stock options and issuances of restricted stock (in shares)		1,982,340
Exercise of stock options and issuances of restricted stock	24,422		24,422
Stock issued for services (in shares)		1,145
Stock issued for services	82		82
Share-based compensation	64,035		64,035
Net loss	(74,676)			(74,676)
Other comprehensive (loss) income	87				87
Balance, shares (in shares) at Dec. 31, 2024		106,240,009
Balance at Dec. 31, 2024	$ 1,148,460	$ 11	$ 2,840,094	$ (1,691,836)	$ 191