Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Total revenues, net	$ 680,852	$ 464,370	$ 250,314
Operating expenses:
Cost of product sales	56,963	33,745	20,443
Selling, general and administrative	504,489	409,864	358,782
Research and development	236,121	180,142	134,715
Total operating expenses	797,573	623,751	513,940
Loss from operations	(116,721)	(159,381)	(263,626)
Interest income	42,518	20,343	7,376
Loss before provision for income taxes	(74,203)	(139,038)	(256,250)
Income tax expense	(473)	(636)	(6)
Net loss	$ (74,676)	$ (139,674)	$ (256,256)
Net loss per common share:
Basic (in dollars per share)	$ (0.72)	$ (1.46)	$ (2.72)
Diluted (in dollars per share)	$ (0.72)	$ (1.46)	$ (2.72)
Weighted average number of common shares:
Basic (in shares)	103,131,017	95,881,729	94,046,670
Diluted (in shares)	103,131,017	95,881,729	94,046,670
Product sales, net
Total revenues, net	$ 680,501	$ 462,175	$ 249,132
Grant revenue
Total revenues, net	$ 351	$ 2,195	$ 1,182