Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Total revenues, net	$ 110,792	$ 55,579	$ 206,098	$ 90,575
Operating expenses:
Cost of product sales	7,163	4,650	13,914	7,805
Selling, general and administrative	101,014	100,316	199,937	175,776
Research and development	49,794	38,536	87,818	67,579
Total operating expenses	157,971	143,502	301,669	251,160
Loss from operations	(47,179)	(87,923)	(95,571)	(160,585)
Interest income	4,530	1,320	8,879	1,868
Loss before provision for income taxes	(42,649)	(86,603)	(86,692)	(158,717)
Income tax expense	(135)	0	(145)	(5)
Net loss	$ (42,784)	$ (86,603)	$ (86,837)	$ (158,722)
Net loss per common share:
Basic (in dollars per share)	$ (0.45)	$ (0.92)	$ (0.91)	$ (1.70)
Diluted (in dollars per share)	$ (0.45)	$ (0.92)	$ (0.91)	$ (1.70)
Weighted average number of common shares:
Basic (in shares)	95,948,063	94,285,117	95,543,626	93,449,424
Diluted (in share)	95,948,063	94,285,117	95,543,626	93,449,424
Product sales, net
Total revenues, net	$ 110,128	$ 55,074	$ 204,859	$ 89,829
Grant revenue
Total revenues, net	$ 664	$ 505	$ 1,239	$ 746