Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Comprehensive Loss
Beginning balance at Dec. 31, 2021	$ 417,890	$ 8	$ 1,639,476	$ (1,221,230)	$ (364)
Beginning balance (in shares) at Dec. 31, 2021		81,886,965
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common shares issued (in shares)		10,952,381
Common shares issued	433,725	$ 1	433,724
Exercise of stock options and issuances of restricted stock (in shares)		1,180,696
Exercise of stock options and issuances of restricted stock	8,089		8,089
Stock issued for services (in shares)		383
Stock issued for services	24		24
Share-based compensation	8,105		8,105
Net loss	(72,119)			(72,119)
Other comprehensive loss	(2,964)				(2,964)
Ending balance at Mar. 31, 2022	792,750	$ 9	2,089,418	(1,293,349)	(3,328)
Ending balance (in shares) at Mar. 31, 2022		94,020,425
Beginning balance at Dec. 31, 2022	656,070	$ 9	2,137,737	(1,477,486)	(4,190)
Beginning balance (in shares) at Dec. 31, 2022		94,829,794
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Exercise of stock options and issuances of restricted stock (in shares)		849,827
Exercise of stock options and issuances of restricted stock	3,640	$ 1	3,639
Stock issued for services (in shares)		408
Stock issued for services	22		22
Share-based compensation	10,439		10,439
Net loss	(44,053)			(44,053)
Other comprehensive loss	1,492				1,492
Ending balance at Mar. 31, 2023	$ 627,610	$ 10	$ 2,151,837	$ (1,521,539)	$ (2,698)
Ending balance (in shares) at Mar. 31, 2023		95,680,029