Commitments and Contingencies - Additional Information (Detail) - USD ($) $ in Thousands		3 Months Ended		214 Months Ended
	May 31, 2005	Mar. 31, 2023	Mar. 31, 2022	Mar. 31, 2023	Dec. 31, 2022
Purchase Commitment
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Cash paid		$ 23,000		$ 23,000	$ 21,600
Product | Bristol-Myers Squibb Company
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Company made an upfront payment				10,750
Payment of milestone amount		$ 5,000		$ 5,000
Obliged to make milestone payments	$ 14,750
License expiration period		10 years
Cost of product sales		$ 4,700	$ 1,700
Product | Bristol-Myers Squibb Company | Minimum
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Royalty payment, percentage (as a percent)	5.00%
Product | Bristol-Myers Squibb Company | Maximum
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Royalty payment, percentage (as a percent)	9.00%