X0306 4 2022-03-10 0 0001567514 Intra-Cellular Therapies, Inc. ITCI 0001585699 Mates Sharon C/O INTRA-CELLULAR THERAPIES, INC. 430 EAST 29TH STREET NEW YORK NY 10016 1 1 0 0 Chairman, President & CEO Stock Option (right to buy) 56.73 2022-03-10 4 A 0 50167 0.00 A 2032-03-09 Common Stock 50167 50167 D Restricted Stock Units 2022-03-10 4 A 0 61696 0.00 A Common Stock 61696 61696 D On March 10, 2022, the reporting person was granted options to purchase 50,167 shares of common stock, vesting in three equal annual installments beginning on the first anniversary of the grant date. Each restricted stock unit represents a contingent right to receive one share of common stock. On March 10, 2022, the reporting person was granted 61,696 restricted stock units, vesting in three equal annual installments beginning on the first anniversary of the grant date. /s/ Lawrence J. Hineline, Attorney-in-fact 2022-03-14