X0306 4 2022-01-18 0 0001567514 Intra-Cellular Therapies, Inc. ITCI 0001829958 Durgam Suresh K. C/O INTRA-CELLULAR THERAPIES, INC. 430 EAST 29TH STREET NEW YORK NY 10016 0 1 0 0 Chief Medical Officer Common Stock 2022-01-18 4 S 0 6223 42.03 D 23104 D This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person in 2021. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.92 to $42.06, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above. /s/ Lawrence J. Hineline, Attorney-in-fact 2022-01-20