X0306 4 2021-06-14 0 0001567514 Intra-Cellular Therapies, Inc. ITCI 0001216955 MARCUS JOEL S C/O ALEXANDRIA REAL ESTATE EQUITIES,INC. 26 NORTH EUCLID AVENUE PASADENA CA 91101 1 0 0 0 Common Stock 13767 D Common Stock 2021-06-14 4 M 0 20000 38.35 A 67269 I Held by the Joel S. Marcus and Barbara A. Marcus Family Trust Common Stock 2021-06-14 4 S 0 18289 42.27 D 48980 I Held by the Joel S. Marcus and Barbara A. Marcus Family Trust Common Stock 26916 I See Footnote Common Stock 1164240 I See Footnote Stock Option (right to buy) 38.35 2021-06-14 4 M 0 20000 0.00 D 2026-06-14 Common Stock 20000 0 I Held by the Joel S. Marcus and Barbara A. Marcus Family Trust The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $42.11 to $42.37, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above. Represents securities held of record by Alexandria Real Estate Equities, Inc. The reporting person is the Executive Chairman & Founder of Alexandria Real Estate Equities, Inc. and may therefore be deemed to have voting and investment power with respect to the shares owned by Alexandria Real Estate Equities, Inc. The reporting person disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Represents securities held of record by Alexandria Venture Investments, LLC ("Alexandria"). Alexandria Real Estate Equities, Inc. is the managing member of Alexandria. Each of Alexandria and Alexandria Real Estate Equities, Inc. has shared voting and investment power with respect to the shares owned by Alexandria. The reporting person is the Executive Chairman of Alexandria Real Estate Equities, Inc. and may therefore be deemed to have voting and investment power with respect to the shares owned by Alexandria. Each of the reporting person and Alexandria Real Estate Equities, Inc. disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. All shares underlying this option have vested. /s/ Lawrence J. Hineline, Attorney-in-fact 2021-06-15