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Net Loss Per Share - Antidilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Unexercised stock options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computation of earnings per share (shares) 14,475,636 10,025,124
Unvested restricted stock units    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computation of earnings per share (shares) 119,705 253,308
Convertible notes    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from computation of earnings per share (shares) 35,732,853 8,815,655