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Income Taxes - Effective Income Tax Reconciliation (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
United States federal tax at statutory rate 21.00% 21.00%
Items affecting federal income tax rate:    
State tax, net of federal benefit 6.51% 3.44%
Valuation allowance (37.34%) (23.07%)
R&D Credit 9.47% 0.00%
NOL Expiration (1.69%) (0.41%)
Other adjustments 1.89% (1.47%)
Effective income tax rate (0.16%) (0.51%)