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Property, Plant and Equipment, net
12 Months Ended
Dec. 31, 2021
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment, net Property, Plant and Equipment, net
Property, plant and equipment, net as of December 31, 2021 and 2020 consisted of the following:
December 31,
Useful life (in years)20212020
Computer equipment and software
3 - 5
$9,267 $12,332 
Furniture and equipment
5 - 7
1,060 1,168 
Leasehold and building improvements (1)
3,821 4,282 
Property, plant, and equipment, excluding internal-use software14,148 17,782 
Less: Accumulated depreciation and amortization(10,857)(12,837)
Property, plant and equipment, excluding internal-use software, net3,291 4,945 
Internal-use software
3
43,314 38,488 
Construction in progress - Internal-use software1,082 1,616 
Less: Accumulated depreciation and amortization - internal-use software(35,321)(31,947)
Internal-use software, net9,075 8,157 
Property, plant and equipment, net$12,366 $13,102 
(1) Useful lives for leasehold and building improvements represent the term of the lease or the estimated life of the related improvements, whichever is shorter.
Depreciation expense from continuing operations was $5,932 and $7,394 for the years ended December 31, 2021 and 2020, respectively, of which $4,027 and $5,743, respectively, related to internal-use software costs.

Amounts capitalized to internal-use software related to continuing operations for the years ended December 31, 2021 and 2020 were $4,727 and $3,437, respectively.

In the fourth quarter of 2020, the Company’s discussions with and exploration of potential opportunities for its sequencing and molecular analysis solutions indicated that certain internal-use software developed by the Company related to its GPS Cancer product would not be utilized in those arrangements. As a result, the Company determined that the carrying value of these internal-use software assets was not recoverable as of December 31, 2020 and recorded an impairment loss of $729 within impairment of intangible assets, including internal-use software.