X0202 SCHEDULE 13G/A 0002140685-26-000001 0002140685 XXXXXXXX LIVE 1 common stock, par value $0.0001 07/13/2026 0001566044 VYNE Therapeutics Inc. 92941V308 685 ROUTE 202/206 N., SUITE 301 685 ROUTE 202/206 N., SUITE 301 BRIDGEWATER NJ 08807 Rule 13d-1(c) Zhang Xiaofan VYNE Therapeutics Inc. 685 ROUTE 202/206 N., SUITE 301, 685 ROUTE 202/206 N., SUITE 301, BRIDGEWATER, NEW JERSEY, 08807. zhang xiaofan Rm1607, tower 3, central residence, 1038 Huashan Road, Shanghai hong kong Y 4595118 13.8% 4595118 4595118 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Zhang Xiaofan zhang xiaofan 07/14/2026