CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common stock	Additional paid-in capital	Accumulated other comprehensive income (loss)	Accumulated deficit
Beginning balance ( in shares) at Dec. 31, 2023		14,098,888
Beginning balance at Dec. 31, 2023	$ 88,735	$ 1	$ 780,044	$ 26	$ (691,336)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(15,655)				(15,655)
Vesting of restricted stock units, net of withholding for tax and shares issued under employee stock purchase plan (in shares)		10,686
Vesting of restricted stock units, net of withholding for tax, and shares issued under employee stock purchase plan	3		3
Stock-based compensation	1,870		1,870
Cashless exercise of pre-funded warrants ( in shares)		426,550
Unrealized losses from marketable securities	(84)			(84)
Ending balance ( in shares) at Jun. 30, 2024		14,536,124
Ending balance at Jun. 30, 2024	74,869	$ 1	781,917	(58)	(706,991)
Beginning balance ( in shares) at Mar. 31, 2024		14,301,688
Beginning balance at Mar. 31, 2024	83,370	$ 1	781,024	(70)	(697,585)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(9,406)				(9,406)
Vesting of restricted stock units, net of withholding for tax and shares issued under employee stock purchase plan (in shares)		7,877
Vesting of restricted stock units, net of withholding for tax, and shares issued under employee stock purchase plan	8		8
Stock-based compensation	885		885
Cashless exercise of pre-funded warrants ( in shares)		226,559
Unrealized losses from marketable securities	12			12
Ending balance ( in shares) at Jun. 30, 2024		14,536,124
Ending balance at Jun. 30, 2024	$ 74,869	$ 1	781,917	(58)	(706,991)
Beginning balance ( in shares) at Dec. 31, 2024	14,830,013	14,830,013
Beginning balance at Dec. 31, 2024	$ 52,086	$ 1	783,235	20	(731,170)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(14,366)				(14,366)
Vesting of restricted stock units, net of withholding for tax and shares issued under employee stock purchase plan (in shares)		130,160
Vesting of restricted stock units, net of withholding for tax, and shares issued under employee stock purchase plan	(109)		(109)
Stock-based compensation	1,292		1,292
Cashless exercise of pre-funded warrants ( in shares)		4,813,611
Cashless exercise of pre-funded warrants	1	$ 1
Unrealized losses from marketable securities	$ (22)			(22)
Ending balance ( in shares) at Jun. 30, 2025	19,773,784	19,773,784
Ending balance at Jun. 30, 2025	$ 38,882	$ 2	784,418	(2)	(745,536)
Beginning balance ( in shares) at Mar. 31, 2025		15,959,488
Beginning balance at Mar. 31, 2025	44,132	$ 2	783,911	0	(739,781)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(5,755)				(5,755)
Vesting of restricted stock units, net of withholding for tax and shares issued under employee stock purchase plan (in shares)		48,976
Vesting of restricted stock units, net of withholding for tax, and shares issued under employee stock purchase plan	(22)		(22)
Stock-based compensation	529		529
Cashless exercise of pre-funded warrants ( in shares)		3,765,320
Unrealized losses from marketable securities	$ (2)			(2)
Ending balance ( in shares) at Jun. 30, 2025	19,773,784	19,773,784
Ending balance at Jun. 30, 2025	$ 38,882	$ 2	$ 784,418	$ (2)	$ (745,536)