CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Total Revenues	$ 14,755,000	$ 20,993,000
Cost of goods sold	3,348,000	1,392,000
Operating Expenses:
Research and development	24,958,000	43,533,000
Selling, general and administrative	54,481,000	89,543,000
Goodwill and in-process research & development impairments	0	54,345,000
Contingent Stock Remeasurement	0	84,726,000
Total Operating Expenses	79,439,000	272,147,000
Operating Loss	68,032,000	252,546,000
Interest expense	5,610,000	4,390,000
Other expense (income), net	135,000	(1,110,000)
Loss Before Income Tax	73,777,000	255,826,000
Income Tax (Benefit) Expense (Note 16)	(448,000)	(258,000)
Net Loss	$ 73,329,000	$ 255,568,000
Loss per share basic (in dollars per share)	$ 1.42	$ 7.88
Loss per share diluted (in dollars per share)	$ 1.42	$ 7.88
Weighted average shares outstanding - basic (in shares)	51,469	32,418
Weighted average shares outstanding - diluted (in shares)	51,469	32,418
Product sales, net
Total Revenues	$ 13,824,000	$ 10,202,000
License revenues
Total Revenues	0	10,000,000
Royalty revenues
Total Revenues	$ 931,000	$ 791,000