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Significant Accounting Policies - Net Loss per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Accounting Policies [Abstract]    
Net loss attributable to common stockholders, basic $ (12,657) $ (5,474)
Weighted‑average common shares outstanding (shares) 17,709,274 5,280,058
Less: weighted‑average common shares subject to repurchase (shares) (125,897) (208,337)
Weighted‑average number of common shares used to compute basic and diluted net loss per share (in shares) 17,583,377 5,071,721
Basic and diluted (in USD per share) $ (0.72) $ (1.08)
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Potentially dilutive securities excluded from the calculation of EPS 6,355,952 8,155,676
Stock options available for issuance    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Potentially dilutive securities excluded from the calculation of EPS 3,731,172 1,123,911
Stock options outstanding    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Potentially dilutive securities excluded from the calculation of EPS 2,505,754 1,595,499
Outstanding common stock subject to repurchase    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Potentially dilutive securities excluded from the calculation of EPS 119,026 201,466
Convertible preferred stock issuable upon conversion to common stock    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Potentially dilutive securities excluded from the calculation of EPS 0 5,234,800