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Stockholders' Equity (Deficit) (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 31, 2018
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Jan. 23, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Total stock-based compensation expense   $ 994 $ 589 $ 2,564 $ 1,217  
Research and development            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Total stock-based compensation expense   475 322 1,217 676  
General and administrative            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Total stock-based compensation expense   $ 519 $ 267 $ 1,347 $ 541  
2011 Stock Incentive Plan | Stock Options            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Option expiration period       10 years    
Option vesting period       4 years    
2018 Omnibus Incentive Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available under the Plan (shares)           3,000,000
Shares available for issuance under the Plan (shares)   2,195,901   2,195,901    
2018 Employee Stock Purchase Plan            
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]            
Shares available under the Plan (shares) 325,000          
Purchase of common stock offer period under the plan 6 months          
Discount rate from price of common stock on purchase date 15.00%          
Commencement date to purchase common stock under the ESPP Sep. 01, 2018