<SEC-DOCUMENT>0000929638-23-003080-index.html : 20231113
<SEC-HEADER>0000929638-23-003080.hdr.sgml : 20231113
<ACCEPTANCE-DATETIME>20231113160340
ACCESSION NUMBER:		0000929638-23-003080
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20231113
DATE AS OF CHANGE:		20231113
GROUP MEMBERS:		BIHUA CHEN
GROUP MEMBERS:		CORMORANT GLOBAL HEALTHCARE GP, LLC
GROUP MEMBERS:		CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VYNE Therapeutics Inc.
		CENTRAL INDEX KEY:			0001566044
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453757789
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-90268
		FILM NUMBER:		231398512

	BUSINESS ADDRESS:	
		STREET 1:		685 ROUTE 202/206 N., SUITE 301
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807
		BUSINESS PHONE:		800-775-7936

	MAIL ADDRESS:	
		STREET 1:		685 ROUTE 202/206 N., SUITE 301
		CITY:			BRIDGEWATER
		STATE:			NJ
		ZIP:			08807

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Menlo Therapeutics Inc.
		DATE OF NAME CHANGE:	20180201

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Menlo Therapeutics, Inc.
		DATE OF NAME CHANGE:	20170728

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Tigercat Pharma, Inc.
		DATE OF NAME CHANGE:	20130104

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cormorant Asset Management, LP
		CENTRAL INDEX KEY:			0001583977
		IRS NUMBER:				462108927
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		857-702-0388

	MAIL ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cormorant Asset Management, LLC
		DATE OF NAME CHANGE:	20130807
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>schedule13g.htm
<TEXT>
Document 1 - file: schedule13g.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>exhibit99-1.htm
<DESCRIPTION>JOINT FILING AGREEMENT BY AND AMONG THE REPORTING PERSONS
<TEXT>
Document 2 - file: exhibit99-1.htm

</DOCUMENT>
</SEC-DOCUMENT>