X0306 4 2020-09-19 0 0001750284 Olema Pharmaceuticals, Inc. OLMA 0001564621 Moriarty John B C/O OLEMA PHARMACEUTICALS, INC. 512 2ND STREET, 4TH FLOOR SAN FRANCISCO CA 94107 0 1 0 0 EVP, Ch. Legal Officer & Sec. Stock Option (Right to Buy) 4.824 2020-09-19 4 A 0 252060 0.00 A 2030-09-18 Common Stock 252060 252060 D Stock Option (Right to Buy) 19.00 2020-11-18 4 A 0 161406 0.00 A 2030-11-17 Common Stock 161406 161406 D 25% of the shares subject to the option vest on September 8, 2021 and 1/48 of the total number of shares subject to the option vest each month thereafter, subject to the Reporting Person's continuous service through each applicable vesting date. The stock option is early exercisable. 25% of the shares subject to the option vest on November 18, 2021 and 1/48 of the total number of shares subject to the option vest each month thereafter, subject to the Reporting Person's continuous service through each applicable vesting date. /s/ John B. Moriarty, Jr. 2020-11-19