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Income Taxes - Reconciliation Between Income Tax Benefit and Expected Tax Benefit at Statutory Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 21.00%
State income tax benefit—net of federal tax 6.00% 6.10%
Change in valuation allowance (29.10%) (29.10%)
Refundable tax credit 0.10% 0.10%
R&D tax credits 2.10% 2.00%
Effective income tax rate 0.10% 0.10%