Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 36,830	$ 45,001
Prepaid expenses	886	1,003
Other current assets	241	265
Total current assets	37,957	46,269
Other non-current assets	334	532
Operating lease right-of-use asset	131	227
Property, equipment and leasehold improvements, net	53	103
Total assets	38,475	47,131
Current liabilities:
Accounts payable	2,849	2,016
Accrued expenses	3,808	3,426
Term loan	5,833
Term loan derivative liability	114
Operating lease liability	120	113
Total current liabilities	12,724	5,555
Term loan	8,652	13,954
Term loan derivative liability		196
Operating lease liability	24	144
Total liabilities	21,400	19,849
Commitments and contingencies (Note 11)
Stockholders’ equity:
Preferred stock: $0.001 par value; 5,000,000 shares authorized at December 31, 2021 and December 31, 2020; no shares issued or outstanding at December 31, 2021 or December 31, 2020.
Common stock: $0.001 par value; 200,000,000 shares authorized at December 31, 2021 and December 31, 2020; and 28,505,804 and 18,546,786 shares issued and outstanding at December 31, 2021 and December 31, 2020, respectively.	29	19
Additional paid-in capital	197,963	174,240
Accumulated deficit	(180,917)	(146,977)
Total stockholders’ equity	17,075	27,282
Total liabilities and stockholders’ equity	$ 38,475	$ 47,131