X0206 3 2019-05-07 0 0001563880 Trevi Therapeutics, Inc. TRVI 0001229245 GOOD JENNIFER L C/O TREVI THERAPEUTICS, INC. 195 CHURCH STREET, 14TH FLOOR NEW HAVEN CT 06510 1 1 1 0 See Remarks Common Stock 176606 D Series A Preferred Stock Common Stock 15549 D Series C Preferred Stock Common Stock 2795 D Employee Stock Option (right to buy) 3.14 2023-07-10 Common Stock 12257 D Employee Stock Option (right to buy) 3.14 2023-12-09 Common Stock 2451 D Employee Stock Option (right to buy) 3.23 2024-01-22 Common Stock 13547 D Employee Stock Option (right to buy) 2.19 2024-07-01 Common Stock 62804 D Employee Stock Option (right to buy) 1.43 2024-11-24 Common Stock 61180 D Employee Stock Option (right to buy) 1.43 2025-05-14 Common Stock 5263 D Employee Stock Option (right to buy) 3.33 2027-12-19 Common Stock 173684 D The Series A Preferred Stock and the dividends that have accrued thereon to date are convertible on a 9.5-for-one basis into the number of shares of Common Stock shown in Column 3 without payment of further consideration at the holder's election or automatically upon the closing of the Issuer's initial public offering. The number of shares of Common Stock into which the Series A Preferred Stock and accrued dividends thereon are convertible will increase on a daily basis without payment of further consideration as additional dividends accrue. The shares have no expiration date. The Series C Preferred Stock and the dividends that have accrued thereon to date are convertible on a 9.5-for-one basis into the number of shares of Common Stock shown in Column 3 without payment of further consideration at the holder's election or automatically upon the closing of the Issuer's initial public offering. The number of shares of Common Stock into which the Series C Preferred Stock and accrued dividends thereon are convertible will increase on a daily basis without payment of further consideration as additional dividends accrue. The shares have no expiration date. This option was granted on July 11, 2013. The 12,257 shares of common stock underlying the option vested as to 25% of the shares on July 11, 2014 and as to the remaining 75% of the shares in equal monthly installments thereafter through July 11, 2017. This option was granted on December 10, 2013. The 2,451 shares of common stock underlying the option vested as to 25% of the shares on December 10, 2014 and as to the remaining 75% of the shares in equal monthly installments thereafter through December 10, 2017. This option was granted on January 23, 2014. The 13,547 shares of common stock underlying the option vested as to 25% of the shares on January 23, 2015 and as to the remaining 75% of the shares in equal monthly installments thereafter through January 23, 2018. This option was granted on July 2, 2014. The 62,804 shares of common stock underlying the option vested as to 25% of the shares on June 11, 2015 and as to the remaining 75% of the shares in equal monthly installments thereafter through June 11, 2018. This option was granted on November 25, 2014. The 61,180 shares of common stock underlying the option vested as to 25% of the shares on November 25, 2015 and as to the remaining 75% of the shares in equal monthly installments thereafter through November 25, 2018. This option was granted on May 15, 2015. The 5,263 shares of common stock underlying the option vested as to 25% of the shares on May 15, 2016 and are scheduled to vest as to the remaining 75% of the shares in equal monthly installments thereafter through May 15, 2019. This option was granted on December 20, 2017. The 173,684 shares of common stock underlying the option vested as to 25% of the shares on December 20, 2018 and are scheduled to vest as to the remaining 75% of the shares in equal monthly installments thereafter through December 20, 2021. Exhibit Index: 24.1 Power of Attorney President and Chief Executive Officer /s/ Jennifer L. Good 2019-05-07