Note 13 - Purchase Commitments

6 Months Ended

Jun. 30, 2014

Commitments and Contingencies Disclosure [Abstract]

Commitments and Contingencies Disclosure [Text Block]

13. Purchase Commitments

The Company is required to schedule its manufacturing activities in advance. If the Company cancels any of these scheduled activities without proper notice the Company would be required to pay penalties equal to the cost of the originally scheduled activity. The Company estimates that the cost of these penalties would be approximately $0.1 million at June 30, 2014 if the Company cancels the scheduled activities. The amounts recorded under this manufacturing contract included in research and development was $0.8 million and $14,000 for the three months ended June 30, 2014 and 2013, respectively and $2.6 million and $0.9 million for the six months ended June 30, 2014 and 2013, respectively.