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Share-Based Compensation - Stock option and restricted stock unit activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2022
Dec. 31, 2021
Amount, Outstanding 2,501,419  
Amount, Granted 427,390  
Amount, Outstanding 1,888,622 2,501,419
Weighted-average exercise price, Outstanding $ 4.35  
Weighted-average exercise price, Granted 8.88  
Weighted-average exercise price, Outstanding $ 3.58 $ 4.35
Biostage2013 Equity Incentive Plan [Member] | Stock Options [Member]    
Amount, Outstanding 2,332,603  
Amount, Granted 189,828  
Amount, Canceled / forfeited (50,097)  
Amount, Outstanding 2,472,334 2,332,603
Amount, Options exercisable 1,197,964  
Amount, Options vested and expected to vest 2,387,217  
Weighted-average exercise price, Outstanding $ 3.93  
Weighted-average exercise price, Granted 4.67  
Weighted-average exercise price, Canceled / forfeited 2.70  
Weighted-average exercise price, Outstanding 3.88 $ 3.93
Weighted-average exercise price, Options exercisable 5.19  
Weighted-average exercise price, Options vested and expected to vest $ 3.92  
Weighted-average contractual life, Outstanding 8 years 1 month 9 days 8 years 3 months 18 days
Weighted-average contractual life, Options exercisable 7 years 7 months 20 days  
Outstanding at the beginning (in dollars) $ 129  
Outstanding at the end (in dollars) 4,966 $ 129
Exercisable at the end (in dollars) $ 2,419