X0306 4 2021-09-01 0 0001563577 Galera Therapeutics, Inc. GRTX 0001227367 HOLMLUND JON T C/O GALERA THERAPEUTICS, INC., 2 W LIBERTY BLVD #100 MALVERN PA 19355 0 1 0 0 Chief Medical Officer Common Stock 2021-09-01 4 M 0 47756 2.43 A 47756 D Common Stock 2021-09-01 4 S 0 47756 8.4701 D 0 D Stock Option 2.43 2021-09-01 4 M 0 47756 0.00 D 2026-03-31 Common Stock 47756 61142 D The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 18, 2019. The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $8.11 to $9.00. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The option has fully vested and is currently exercisable. /s/ Christopher Degnan, Attorney-in-Fact for Jon T. Holmlund 2021-09-03