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Commitments and Contingencies (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Jun. 30, 2025
ft²
Oct. 31, 2023
USD ($)
ft²
Aug. 31, 2012
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 01, 2023
ft²
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Contingencies and Commitments                
Operating lease cost       $ 300 $ 300      
Operating lease payments made       400 300      
Operating Lease, Liability, Current       $ 565 $ 340      
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]       Accrued Liabilities, Current Accrued Liabilities, Current      
Operating Lease, Liability, Noncurrent       $ 1,700        
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]       Other Liabilities, Noncurrent        
Lease Amendment                
Contingencies and Commitments                
Additional space leased | ft²   15,881            
Lease space relinquished | ft² 4,652              
Area (sqft) | ft² 35,954 24,725       40,606    
Additional security deposit   $ 300            
Pennsylvania | Office and laboratory space                
Contingencies and Commitments                
Lessee, Operating Lease, Existence of Option to Extend [true false]       true        
Renewal term of operating lease       60 months        
Incremental borrowing rate           11.66%    
Remaining lease term       6 years 4 months 24 days        
Umbrella Agreement with Aroa                
Contingencies and Commitments                
Payment for agreement     $ 4,000          
Milestone payments related to research and development arrangements       $ 1,800        
Fixed Cost Of Net Sales       27.00%        
Number of days for product supply       60 days        
Percentage of products ordered to be supplied       75.00%        
Royalty percentage of net sales       6.00%        
Umbrella Agreement with Aroa | European territory                
Contingencies and Commitments                
Sales milestone payments due         $ 1,000      
Umbrella Agreement with Aroa | North American territory                
Contingencies and Commitments                
Sales milestone payment             $ 2,000 $ 1,000
Transfer Price For Product Produced       200.00%        
Transfer price for product produced for use in IHR       150.00%        
Fixed Cost Of Net Sales       27.00%        
Other Suppliers for Exclusivity Rights [Member]                
Contingencies and Commitments                
Payments To Maintain Exclusivity       $ 7,100