Leases - Narratives (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended
	Dec. 31, 2020	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022	Jan. 01, 2022
Lessee, Lease, Description [Line Items]
Lease liability		$ 1,520
Right-of-use assets		1,187		$ 1,227
Operating lease cost		100	$ 100
Operating lease payments made		100	$ 100
Operating Lease, Liability, Current		$ 342		$ 340
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]		Accrued Liabilities, Current
Operating Lease, Liability, Noncurrent		$ 1,200
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]		Other Liabilities, Noncurrent
Office and laboratory space | Pennsylvania
Lessee, Lease, Description [Line Items]
Lessee, Operating Lease, Existence of Option to Extend [true false]	true
Renewal term of operating lease	60 months
Incremental borrowing rate					9.75%
Remaining lease term		5 years 2 months 12 days