Long-term Debt - Schedule of long term debt (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Debt
Longterm debt with related party	$ 31,669	$ 31,491
OrbiMed Term Loans (related party)
Debt
Long Term Debt	30,000	30,000
End of term charge	3,000	3,000
Unamortized end of term charge and issuance costs	(1,331)	(1,509)
Longterm debt with related party	$ 31,669	$ 31,491