Leases - Narratives (Details) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended
	Jan. 01, 2022	Dec. 31, 2020	Mar. 31, 2022
Lessee, Lease, Description [Line Items]
Lease liability			$ 1,711
Right-of-use asset			1,339
Operating lease cost			100
Operating lease payments made			100
Operating Lease, Liability, Current			$ 347
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]			Accrued And Other Liabilities, Current
Operating Lease, Liability, Noncurrent			$ 1,400
Office and laboratory space | Pennsylvania
Lessee, Lease, Description [Line Items]
Lessee, Operating Lease, Existence of Option to Extend [true false]		true
Renewal term of operating lease		60 months
Incremental borrowing rate	9.75%
Remaining lease term			6 years 2 months 12 days
Office and laboratory space | Pennsylvania | ASU 2016-02 | Cumulative Effect, Period of Adoption, Adjustment [Member]
Lessee, Lease, Description [Line Items]
Lease liability	$ 1,800
Right-of-use asset	1,400
Deferred rent and tenant allowance netted off against right-of-use asset	$ 400