Debt - Schedule of long term debt (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Debt
Longterm debt with related party	$ 31,491	$ 30,827
OrbiMed Term Loans (related party)
Debt
Long Term Debt	30,000	30,000
End of term charge	3,000	3,000
Unamortized end of term charge and issuance costs	(1,509)	(2,173)
Longterm debt with related party	$ 31,491	$ 30,827