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Contingencies and Commitments - Agreement with Aroa (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Apr. 30, 2014
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Contingencies and Commitments        
Agreement extended term   10 years    
Issuance of common stock   $ 44,722 $ 50,629  
Umbrella Agreement with Aroa        
Contingencies and Commitments        
Payment for agreement $ 4,000      
Fixed Cost Of Net Sales   27.00%    
Purchase commitments   $ 4,300    
Number of days for product supply   60 days    
Percentage of products ordered to be supplied   75.00%    
Royalty percentage of net sales   6.00%    
Percentage Paid By Company For Capital Costs Of Any Manufacturing Expansion Plan Agreed Upon By The Parties Under Agreement   50.00%    
Umbrella Agreement with Aroa | European territory        
Contingencies and Commitments        
Developed right intangible asset       $ 1,000
Payments made upon approval     500 500
Sales milestone payments due       1,000
Purchase commitments   $ 2,800    
Purchase Commitments Due Year One And Two From Contract Date   500    
Purchase Commitments Due Year Three From Contract Date   500    
Purchase Commitments Due Year Four From Contract Date   800    
Purchase Commitments Due Year Five From Contract Date   1,000    
Purchase commitments due year Six   $ 1,000    
Payment for extending deadlines to file an investigational device exemption with the FDA     500  
Umbrella Agreement with Aroa | North American territory        
Contingencies and Commitments        
Liability recognized       3,000
Developed right intangible asset       3,000
Sales milestone payment     $ 2,000 1,000
Sales milestone payments due       $ 2,000
Increase in transfer price quarterly percentage   200.00% 150.00%  
Fixed Cost Of Net Sales   27.00%    
Purchase commitments   $ 11,000    
Purchase Commitments Due Year One And Two From Contract Date   2,000    
Purchase Commitments Due Year Three From Contract Date   2,000    
Purchase Commitments Due Year Four From Contract Date   3,000    
Purchase Commitments Due Year Five From Contract Date   4,000    
Purchase commitments due year Six   $ 5,000