Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Property and Equipment
Property and Equipment, Total	$ 4,198	$ 4,001
Less accumulated depreciation and amortization	(3,521)	(3,243)
Property and equipment, net	677	758
Depreciation expense	278	463	$ 761
Umbrella Agreement with Aroa
Property and Equipment
Property and Equipment, Total	200	200
Lab equipment
Property and Equipment
Property and Equipment, Total	$ 2,250	2,203
Estimated useful lives	5 years
Furniture and fixtures
Property and Equipment
Property and Equipment, Total	$ 112	110
Estimated useful lives	5 years
Computer equipment and software
Property and Equipment
Property and Equipment, Total	$ 508	398
Estimated useful lives	3 years
Leasehold improvements
Property and Equipment
Property and Equipment, Total	$ 1,328	$ 1,290

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

+ References

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