X0306 4 2021-08-17 0 0001559720 Airbnb, Inc. ABNB 0001186045 POWELL CATHERINE C 888 BRANNAN STREET SAN FRANCISCO CA 94103 0 1 0 0 Global Head of Hosting Class A Common Stock 2021-08-17 4 S 0 1 145.04 D 140563 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan. The amount of securities beneficially owned following the transactions reported herein reflects the amount of securities currently beneficially owned by the reporting person, accounting for the transactions reported on the Form 4 filed by the reporting person on August 26, 2021, which did not account for the sale reported herein. /s/ Brian Savage, Attorney-in-fact 2021-08-30