Commitment and Contingencies - Lease Narrative (Details)			1 Months Ended	12 Months Ended
	Oct. 28, 2022 USD ($) ft²	Jul. 18, 2018 ft²	Mar. 31, 2016 ft²	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jul. 31, 2023 USD ($)	Apr. 19, 2023	Apr. 11, 2023	Aug. 01, 2021
Lease Description [Line Items]
Operating Lease (Area) | ft²			128,751
Operating lease right-of-use assets				$ 12,162,000	$ 6,277,000
Operating lease cost				6,300,000	6,300,000	$ 6,300,000
Operating lease payments				6,500,000	6,300,000	6,200,000
Restricted cash				2,200,000
Area of sub-sublease rental | ft²		46,641
Sublease Income				2,800,000	$ 2,900,000	$ 2,900,000
Operating lease, future minimum payment due				$ 14,835,000
Dublin, Ireland
Lease Description [Line Items]
Operating leases, term of contract (in years)								1 year		1 year
Lessee, Operating Lease, Renewal Term									1 year
Brisbane, California
Lease Description [Line Items]
Operating Lease (Area) | ft²	31,157
Operating lease, weighted average remaining lease term				4 years 9 months
Operating lease right-of-use assets							$ 11,400,000
Operating lease cost				$ 1,300,000
Operating lease payments				400,000
Discount rate, percent							5.76%
Tenant improvement allowance	$ 9,300,000
Operating lease, future minimum payment due	14,900,000
Lease liability							$ 3,600,000
Proceeds from tenant allowance				8,200,000
Standby Letters of Credit | Brisbane, California
Lease Description [Line Items]
Line of credit has been used				0
Restricted cash	$ 900,000
Standby Letters of Credit | South San Francisco, CA
Lease Description [Line Items]
Line of credit has been used				0
Restricted cash				$ 1,400,000