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Organization - Additional Information (Detail) - USD ($)
$ in Thousands
Sep. 30, 2020
Dec. 31, 2019
Sep. 30, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Accumulated deficit $ (752,313) $ (671,885)  
Cash and cash equivalents $ 314,525 $ 375,723 $ 390,304