Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 314,525	$ 375,723
Accounts receivable	22	68
Prepaid expenses and other current assets	4,586	2,584
Restricted cash, current	1,352	0
Total current assets	320,485	378,375
Non-current assets:
Property and equipment, net	2,899	3,874
Operating lease right-of-use assets	19,197	23,274
Deferred tax assets	11,524	9,956
Restricted cash, non-current	1,352	2,704
Other non-current assets	327	1,085
Total non-current assets	35,299	40,893
Total assets	355,784	419,268
Current liabilities:
Accounts payable	2,810	1,242
Accrued research and development	7,617	5,826
Income taxes payable, current	258	5
Lease liability, current	5,408	5,101
Other current liabilities	5,629	5,540
Total current liabilities	21,722	17,714
Non-current liabilities:
Deferred revenue, non-current	110,242	110,242
Lease liability, non-current	13,753	17,838
Other liabilities	553	553
Total non-current liabilities	124,548	128,633
Total liabilities	146,270	146,347
Commitments and contingencies (Note 6)
Shareholders’ equity:
Euro deferred shares	0	0
Ordinary shares	399	399
Additional paid-in capital	961,428	944,407
Accumulated deficit	(752,313)	(671,885)
Total shareholders’ equity	209,514	272,921
Total liabilities and shareholders’ equity	$ 355,784	$ 419,268