Net Loss Per Ordinary Share (Tables)

9 Months Ended

Sep. 30, 2020

Earnings Per Share [Abstract]

Calculation of Basic and Diluted Net Income or Loss Per Ordinary Share

Net loss per ordinary share was determined as follows (in thousands, except per share amounts):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2020		2019		2020		2019
Numerator:
Net loss	$	(30,577)	$	(19,448)	$	(80,428)	$	(56,123)
Denominator:
Weighted-average ordinary shares outstanding	39,917		39,897		39,912		39,877
Net loss per share:
Basic and diluted net loss per share	$	(0.77)	$	(0.49)	$	(2.02)	$	(1.41)

Ordinary Shares Equivalent Not Included in Diluted Net Loss Per Share

The equivalent ordinary shares not included in diluted net loss per share because their effect would be anti-dilutive are as follows (in thousands):

	Three Months Ended September 30,		Nine Months Ended September 30,
	2020	2019	2020	2019
Stock options to purchase ordinary shares	8,795	7,185	8,795	7,185