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Net Loss Per Ordinary Share (Tables)
6 Months Ended
Jun. 30, 2020
Earnings Per Share [Abstract]  
Calculation of Basic and Diluted Net Income or Loss Per Ordinary Share
Net loss per ordinary share was determined as follows (in thousands, except per share amounts):
Three Months Ended
June 30,
Six Months Ended
June 30,
2020201920202019
Numerator:
Net loss$(26,282) $(15,810) $(49,851) $(36,675) 
Denominator:
Weighted-average ordinary shares outstanding39,911  39,872  39,910  39,868  
Net loss per share:
Basic and diluted net loss per share$(0.66) $(0.40) $(1.25) $(0.92) 
Ordinary Shares Equivalent Not Included in Diluted Net Loss Per Share
The equivalent ordinary shares not included in diluted net loss per share because their effect would be anti-dilutive are as follows (in thousands):
 Three Months Ended
June 30,
Six Months Ended
June 30,
 2020201920202019
Stock options to purchase ordinary shares8,672  7,168  8,672  7,168