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Stock-Based Awards - Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Options, Number of Shares      
Number of Shares, beginning balance 6,419,455 5,167,164  
Number of Shares, Granted 2,608,700 2,241,550  
Number of Shares, Exercised (162,388) (71,092)  
Number of Shares, Forfeited and cancelled (2,143,800) (918,167)  
Number of Shares, ending balance 6,721,967 6,419,455 5,167,164
Number of Shares, Options vested and expected to vest 6,721,967    
Number of Shares, Options exercisable 3,555,450    
Options, Weighted Average Exercise Price      
Weighted Average Exercise Price, beginning balance (in dollars per share) $ 15.94 $ 16.04  
Weighted Average Exercise Price, Granted (in dollars per share) 1.86 15.62  
Weighted Average Exercise Price, Exercised (in dollars per share) 1.31 1.31  
Weighted Average Exercise Price, Forfeited and cancelled (in dollars per share) 15.06 16.85  
Weighted Average Exercise Price, ending balance (in dollars per share) 11.12 $ 15.94 $ 16.04
Weighted Average Exercise Price, Options vested and expected to vest (in dollars per share) 11.12    
Weighted Average Exercise Price, Options exercisable (in dollars per share) $ 15.39    
Options, Weighted Average Remaining Contractual Term      
Weighted Average Remaining Contractual Term (in years) 6 years 9 months 18 days 7 years 1 month 6 days 7 years 2 months 12 days
Weighted Average Remaining Contractual Term, Options vested and expected to vest (in years) 6 years 9 months 18 days    
Weighted Average Remaining Contractual Term, Options exercisable (in years) 5 years    
Aggregate Intrinsic Value      
Aggregate Intrinsic Value $ 2,968 $ 14 $ 15,288
Aggregate Intrinsic Value, Exercised 285 $ 473  
Aggregate Intrinsic Value, Options vested and expected to vest 2,968    
Aggregate Intrinsic Value, Options exercisable $ 944    
Weighted average grant-date fair value of stock options granted (in dollars per share) $ 1.34 $ 10.98