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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Cash flows from operating activities:    
Net loss $ (59,273) $ (68,061)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 607 726
Stock-based compensation expense 10,226 10,209
Revaluation of contingent consideration (2,400) 22,139
Loss on extinguishment of debt   752
Changes in operating assets and liabilities:    
Accounts receivable 26 (39)
Prepaid expenses and other assets 3,408 (8)
Accounts payable (2,319) 1,293
Accrued expenses 1,273 (2,070)
Net cash used in operating activities (48,452) (35,059)
Cash flows from investing activities:    
Purchases of property and equipment (500) (108)
Purchases of marketable securities (118,729) (199,862)
Proceeds from sales and maturities of marketable securities 129,155 41,514
Net cash provided by (used in) investing activities 9,926 (158,456)
Cash flows from financing activities:    
Repayment of debt   (11,483)
Payments of employee withholding taxes related to restricted stock unit award vesting (34) (3,122)
Proceeds from exercise of employee stock options and the issuance of stock 120 1,459
Net cash provided by financing activities 72,830 225,054
Net increase in cash and cash equivalents 34,304 31,539
Cash and cash equivalents at beginning of period 27,349 22,063
Cash and cash equivalents at end of period 61,653 53,602
Supplemental disclosure of non-cash investing and financing activities:    
Additions to property and equipment included in accounts payable 4  
Public Offering    
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs   $ 238,200
At The Market Offering    
Cash flows from financing activities:    
Proceeds from issuance of common stock, net of issuance costs $ 72,744