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Net Loss per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Numerator:        
Net loss $ (32,740) $ (18,192) $ (94,187) $ (45,589)
Denominator:        
Weighted average common shares outstanding used in calculating net loss per share attributable to common stockholders, basic and diluted 30,982,192 28,834,808 30,938,026 27,180,244
Net loss per share attributable to common stockholders, basic and diluted (in dollars per share) $ (1.06) $ (0.63) $ (3.04) $ (1.68)