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Stock-Based Awards (Details) - shares
9 Months Ended
Jan. 01, 2017
Sep. 30, 2017
Sep. 30, 2016
Jul. 31, 2017
Dec. 31, 2016
Sep. 15, 2015
Stock-based awards            
Options granted (in shares)   617,500        
Options outstanding   3,242,831     2,702,350  
Stock Option Valuation            
Risk-free interest rate (as a percent)   1.89% 1.41%      
Expected term (in years)   6 years 2 months 12 days 6 years 6 months      
Expected volatility (as a percent)   93.84% 96.60%      
Expected dividend yield (as a percent)   0.00% 0.00%      
2017 Inducement Plan            
Stock-based awards            
Number of shares authorized       1,000,000    
Number of shares available for grant   622,452        
2012 Equity Compensation Plan            
Stock-based awards            
Number of shares available for grant   0        
Term of award (in years)   10 years        
Options granted (in shares)   1,140,524        
Options outstanding   1,003,647     1,049,667  
Vesting period (in years)   4 years        
2015 Equity Incentive Plan            
Stock-based awards            
Number of shares authorized           1,643,872
Percentage increase to shares available for grant from common outstanding as of preceding December 31 (as a percent)   4.00%        
Additional shares available 1,042,367          
Number of shares available for grant   1,368,904