CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Operating expenses:
Research and development	$ 7,772	$ 9,535
General and administrative	5,158	3,604
Total operating expenses	12,930	13,139
Loss from operations	(12,930)	(13,139)
Other income, net	371	100
Net loss	$ (12,559)	$ (13,039)
Net loss per share, basic and diluted (in dollars per share)	$ (0.48)	$ (0.65)
Weighted average common shares outstanding, basic and diluted (in shares)	26,080,806	20,171,518
Other comprehensive loss:
Unrealized (loss) gain on marketable securities, net of tax of $0	$ (52)	$ 142
Foreign currency translation adjustments	72	10
Total other comprehensive income	20	152
Comprehensive loss	$ (12,539)	$ (12,887)