Commitments and Contingencies (Details) - USD ($) $ in Thousands	1 Months Ended	12 Months Ended
	Jan. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Supply Agreement
Agreement term (in years)	3 years
Automatic renewal period (in years)		1 year
Termination fee, prior to FDA approval		$ 375
Termination fee, after FDA approval		275
Vixen [Member] | Stock Purchase Agreement [Member]
Supply Agreement
Amount of required annual payment under the contract		100
JAKPharm and Key Organics [Member] | License and collaboration agreement
Agreements for Office Space
Expenses incurred under related party transactions		50
Board of Directors Chairman [Member] | Direct sublease agreement
Agreements for Office Space
Expenses incurred under related party transactions		254	$ 119	$ 66
Future minimum lease payments under the sublease
2017		350
2018		363
2019		339
Total		$ 1,052