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Stock-Based Awards (Details) - shares
12 Months Ended 44 Months Ended
Jan. 01, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Sep. 14, 2015
Oct. 31, 2015
Sep. 15, 2015
Stock-based awards              
Options granted (in shares)   1,083,919 1,238,262 500,262      
Options outstanding   2,702,350 1,738,524 500,262      
Employee, director and consultant stock options              
Stock Option Valuation              
Risk-free interest rate (as a percent)   2.06% 1.78% 1.87%      
Expected term (in years)   6 years 6 months 6 years 3 months 18 days 6 years 4 months 24 days      
Expected volatility (as a percent)   94.86% 93.90% 113.90%      
Expected dividend yield (as a percent)   0.00% 0.00% 0.00%      
2012 Equity Compensation Plan              
Stock-based awards              
Number of shares available for grant           0  
Term of award (in years)   10 years          
Options granted (in shares)         1,140,524    
Options outstanding   1,049,667 1,140,524        
Vesting period (in years)   4 years          
2015 Equity Incentive Plan              
Stock-based awards              
Number of shares authorized             1,643,872
Percentage increase to shares available for grant from common outstanding as of preceding December 31 (as a percent)   4.00%          
Additional shares available 1,042,367            
Number of shares available for grant   607,556          
2015 Equity Incentive Plan | Employee, director and consultant stock options              
Stock-based awards              
Exercise price as percentage of fair market value of common stock at grant date required, minimum   100.00%          
2015 Equity Incentive Plan | Employee, director and consultant stock options | Maximum              
Stock-based awards              
Term of award (in years)   10 years