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Income Taxes (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2015
Dec. 31, 2014
Loss before income taxes                          
U.S. operations                 $ (11,823) $ (8,517) $ (5,236)    
Foreign operations                 (8,740)        
Net loss $ (4,714) $ (10,632) $ (2,594) $ (2,623) $ (2,597) $ (2,657) $ (2,229) $ (1,034) $ (20,563) $ (8,517) $ (5,236)    
Effective Income Tax Rate Reconciliation, Percent [Abstract]                          
Federal statutory income tax rate                 (34.00%) (34.00%) (34.00%)    
State taxes, net of federal benefit                 (3.80%) (6.60%) (6.60%)    
Foreign rate differential                 6.00%        
Research and development tax credits                 (1.50%) (1.00%) (1.60%)    
Change in deferred tax asset valuation allowance                 33.30% 41.60% 42.20%    
Components of net deferred tax assets                          
Net operating loss carryforwards                       $ 5,750 $ 5,606
Capitalized start-up costs                       4,401  
Research and development tax credit carryforwards                       500 203
Capitalized research and development expenses                       611 620
Intangible assets                       1,650  
Stock‑based compensation expenses                       373 11
Other                       1 4
Total deferred tax assets                       13,286 6,444
Valuation allowance (13,286)     (6,444) (6,444)     (2,899) $ (6,444) $ (2,899) $ (690) (13,286) (6,444)
Changes in valuation allowance for deferred tax assets                          
Valuation allowance at beginning of year       $ (6,444)       $ (2,899) (6,444) (2,899) (690)    
Increases recorded to income tax provision                 (6,842) (3,545) (2,209)    
Valuation allowance as of end of year (13,286)       $ (6,444)       (13,286) $ (6,444) $ (2,899)    
Unrecognized Tax Benefits                          
Increases related to prior year tax provisions                 (2,624)        
Increases related to current year tax provisions                 (1,776)        
Unrecognized Tax Benefits, Ending Balance $ (4,400)               (4,400)        
Unrecognized Tax Benefits that Would Impact Effective Tax Rate                       0 $ 0
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense                 $ 0        
Federal                          
Components of net deferred tax assets                          
Net operating loss carryforwards                       13,917  
Research and development tax credit carryforwards                       500  
State                          
Components of net deferred tax assets                          
Net operating loss carryforwards                       13,917  
Research and development tax credit carryforwards                       $ 0