Commitments and Contingencies (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Supply Agreement
Agreement term (in years)	3 years
Automatic renewal period (in years)	1 year
Termination fee, prior to FDA approval	$ 375
Termination fee, after FDA approval	275
Director | Direct sublease agreement
Lease
Expenses incurred under related party transactions	119	$ 66
Future minimum lease payments under the sublease
2016	237
2017	263
2018	268
2019	251
Total	$ 1,019