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Stock-Based Awards (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Sep. 15, 2015
Aug. 25, 2015
Stock-based awards          
Options granted (in shares) 1,238,262 500,262      
Number of Shares          
Number of Shares, beginning balance 500,262        
Number of Shares, Granted 1,238,262 500,262      
Number of Shares, ending balance 1,738,524 500,262      
Number of Shares, Options vested and expected to vest 1,738,524        
Number of Shares, Options exercisable 147,672        
Weighted Average Exercise Price          
Weighted Average Exercise Price, beginning balance (in dollars per share) $ 1.22        
Weighted Average Exercise Price, Granted (in dollars per share) 18.08 $ 1.22      
Weighted Average Exercise Price, ending balance (in dollars per share) 13.23 $ 1.22      
Weighted Average Exercise Price, Options vested and expected to vest (in dollars per share) 13.23        
Weighted Average Exercise Price, Options exercisable (in dollars per share) $ 1.19        
Weighted Average Remaining Contractual Term          
Weighted Average Remaining Contractual Term (in years) 9 years 6 months 4 days 9 years 9 months 7 days      
Weighted Average Remaining Contractual Term, Options vested and expected to vest (in years) 9 years 6 months 4 days        
Weighted Average Remaining Contractual Term, Options exercisable (in years) 8 years 8 months 19 days        
Aggregate Intrinsic Value          
Aggregate Intrinsic Value $ 24,722 $ 305      
Aggregate Intrinsic Value, Options vested and expected to vest 24,722        
Aggregate Intrinsic Value, Options exercisable $ 3,803        
Weighted average grant-date fair value of stock options granted (in dollars per share) $ 13.84 $ 1.38      
Employee, director and consultant stock options          
Stock-based awards          
Options granted (in shares)     0    
Stock Option Valuation          
Risk-free interest rate (as a percent) 1.78% 1.87%      
Expected term (in years) 6 years 3 months 18 days 6 years 4 months 24 days      
Expected volatility (as a percent) 93.90% 113.90%      
Expected dividend yield (as a percent) 0.00% 0.00%      
Expected forfeiture rate (as a percent) 0.00% 0.00%      
Number of Shares          
Number of Shares, Granted     0    
2012 Equity Compensation Plan          
Stock-based awards          
Number of shares authorized   500,262     1,539,169
Number of shares available for grant 0        
2012 Equity Compensation Plan | Maximum          
Stock-based awards          
Term of award (in years) 10 years        
2012 Equity Compensation Plan | Employee, director and consultant stock options          
Stock-based awards          
Exercise price as percentage of fair market value of common stock at grant date required, minimum 100.00%        
Term of award (in years) 10 years        
Vesting period (in years) 4 years        
2015 Equity Incentive Plan          
Stock-based awards          
Number of shares authorized       2,784,395  
Percentage increase to shares available for grant from common outstanding as of preceding December 31 (as a percent)       4.00%