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Quarterly Financial Data (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 7 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Jul. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Net sales $ 187 $ 1,036 $ 1,698 $ 2,336 $ 3,010 $ 4,345 $ 4,967 $ 6,192   $ 5,257 $ 18,514 $ 29,299
License and other revenue 1,277 1,241 1,259 3,230 1,267 1,350 1,453 3,471   7,007 7,541 6,420
Total revenue 1,464 2,277 2,957 5,566 4,277 5,695 6,420 9,663   12,264 26,055 35,719
Cost of sales 222 277 266 567 640 880 880 1,085   1,332 3,485 3,731
Write-down of inventory (22) 933 373 370 119 129 2 135   1,654 385 2,274
Gross profit 1,264 1,067 2,318 4,629 3,518 4,686 5,538 8,443   9,278 22,185 29,714
Research and development 10,499 11,775 10,056 8,447 8,539 9,631 8,587 9,083   40,777 35,840 33,558
Selling, general and administrative 7,916 9,121 9,902 10,118 14,620 48,426 19,148 23,686   37,057 105,880 104,740
Impairment of intangible asset                       31,269
Gain on settlement of payable           (256)   (3,875)     (4,131)  
Total operating expenses 18,415 20,896 19,958 18,565 23,159 57,801 27,735 28,894   77,834 137,589 169,567
Loss from operations (17,151) (19,829) (17,640) (13,936) (19,641) (53,115) (22,197) (20,451)   (68,556) (115,404) (139,853)
Total other expense 1,476 1,874 4,674 3,315 1,716 64,049 14,837 12,407   11,339 93,009 7,232
Income tax expense (benefit) (437)     316 27     315   (121) 342 (3)
Net loss (18,190) (21,703) (22,314) (17,567) (21,384) (117,164) (37,034) (33,173)   (79,774) (208,755) (147,082)
Deemed dividend on convertible preferred stock and Class E redeemable convertible units 490 490 469 469 469 21,264       1,918 21,733  
Net loss attributable to common stockholders $ (18,680) $ (22,193) $ (22,783) $ (18,036) $ (21,853) $ (138,428) [1] $ (37,034) $ (33,173)   $ (81,692) $ (230,488) $ (147,082)
Basic and diluted net loss per share of common stock $ (0.24) $ (0.42) $ (0.44) $ (0.39) $ (0.48) $ (4.24) $ (4.46) $ (4.00)   $ (1.42) $ (9.74) $ (18.10)
Weighted average basic and diluted shares of common stock outstanding 78,397,156 52,572,880 51,846,521 46,507,435 45,078,666 32,678,259 [2] 8,304,334 8,302,635   57,405,331 23,674,512 8,127,781
Beneficial conversion feature expense on convertible debt           $ 44,200         $ 44,170  
Deemed dividends on preferred stock           20,900            
Beneficial conversion feature expense on warrants           1,700         $ 1,745  
2014 Long-Term Incentive Plan (“LTIP”) [Member]                        
Allocated Share-based Compensation Expense           $ 22,600     $ 0      
[1] Net loss attributable to common stockholders for the three months ended September 30, 2016 includes the beneficial conversion feature of the Company's debt upon conversion into shares of the Company's common stock on August 1, 2016 of $44.2 million, the beneficial conversion feature of certain outstanding warrants which became exercisable into shares of the Company's common stock on August 1, 2016 of $1.7 million, the deemed dividends on the Company's convertible preferred stock and Class E redeemable convertible units of $20.9 million and share-based compensation expense related to the Company's LTIP of $22.6 million.
[2] Weighted average basic and diluted shares of common stock outstanding for the three months ended September 30, 2016 includes shares issued as a result of the Corporate Conversion (Note 1).