<SEC-DOCUMENT>0001209191-19-061429-index.html : 20191220
<SEC-HEADER>0001209191-19-061429.hdr.sgml : 20191220
<ACCEPTANCE-DATETIME>20191220081322
ACCESSION NUMBER:		0001209191-19-061429
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20161219
FILED AS OF DATE:		20191220
DATE AS OF CHANGE:		20191220

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Alles Mark J
		CENTRAL INDEX KEY:			0001538897

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37813
		FILM NUMBER:		191297694

	MAIL ADDRESS:	
		STREET 1:		C/O CELGENE CORPORATION
		STREET 2:		86 MORRIS AVENUE
		CITY:			SUMMIT
		STATE:			NJ
		ZIP:			07901

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		35 CAMBRIDGE PARK DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02140

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
Document 1 - file: doc3.html

Document 1 - RAW XML: doc3.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
<TEXT>
Document 2 - file: attachment1.htm

</DOCUMENT>
</SEC-DOCUMENT>