<SEC-DOCUMENT>0001209191-19-010285-index.html : 20190214
<SEC-HEADER>0001209191-19-010285.hdr.sgml : 20190214
<ACCEPTANCE-DATETIME>20190214171847
ACCESSION NUMBER:		0001209191-19-010285
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20190212
FILED AS OF DATE:		20190214
DATE AS OF CHANGE:		20190214

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Roth David
		CENTRAL INDEX KEY:			0001599014

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37813
		FILM NUMBER:		19608344

	MAIL ADDRESS:	
		STREET 1:		C/O SYROS PHARMACEUTICALS, INC.
		STREET 2:		620 MEMORIAL DRIVE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Syros Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001556263
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				453772460
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		620 MEMORIAL DRIVE
		STREET 2:		SUITE 300
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		617-744-1340

	MAIL ADDRESS:	
		STREET 1:		620 MEMORIAL DRIVE
		STREET 2:		SUITE 300
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LS22, Inc.
		DATE OF NAME CHANGE:	20120815
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
Document 1 - file: doc4.html

Document 1 - RAW XML: doc4.xml

</DOCUMENT>
</SEC-DOCUMENT>